What is Leptin hormone

Starting with a link in a easy google search:
http://nutritionwonderland.com/2009/06/understanding-our-bodies-leptin-the-fullness-hormone/

This link explains the other duties of hormone related to appetite control. It also explains why the low calorie diets are failing, because the leptine is produced by the fat cells, and if you loose your fat quickly, the hormone balance is broken, and your body will think something bad happening (like starvation) and slows down your methobolism to reduce energy and try to store as much as possible from the foods to fat. That is also the reason why we cannot just loose fat by a simple surgery on the fat cells.

The reason why the diets are failing and you get back more, is also because of the frequent eating between the meals (although small) which increases the insulin in blood, and creates an insulin resistance in brain and cells.

As you know, the insulin is generated in pancreas, and helps the blood sugar to enter into the cells and as a result be used as energy for the body. But what happens the unused part of this sugar? It is stored as fat to be used later! To store this sugar into fat, insulin hormone opens the doors of fat cells. So, insulin is also responsible for fat storage.

Watch this video to see how the food is converted into glucose (blood sugar) and with the help of insulin it enters into the cell: http://www.youtube.com/watch?v=OYH1deu7-4E

Understanding these details is essential to understand what to eat.

So what happens after you eat:
- The blood sugar (glucose) and insulin increases in blood.
- After 2-3 hour of your eating, insulin goes down, because the glucose is already spent.
- Glucose is used for every activity for your body, reading a book, sleeping, driving... Like the fuel of a car, the glucose is spent with the help of insulin. As you have seen in the video, insulin is like a key that is opening the cell doors.
- When you take more energy (=blood sugar/glucose), the second duty of insulin starts.
- Insulin opens the doors of fat cells, and stores the glucose as trigliseride.
- After 3 hours of eating, pancreas produces glucagon  to give a message to liver for a release of backup blood sugar in liver, so that the extra energy without the food comes from this backup blood sugar. This energy is for a short period. (Keep in mind this step, I will return it shortly)
- For a healthy person, in normal conditions, after you eat, if your hormones are working fine, you should not become hungry for 4 hours.
- After 4 hours, here comes our hero, the leptine hormone.
- The responsibility of leptin hormone is to burn the fats that are stored in different parts of body, for the extra energy required after 4 hours of hunger. (trigliseride to glucose).
- This hormone is also in high levels while you are sleeping for its other duties between 2-5.

If you eat between the meals, you break the producing of leptine hormone. While the insulin levels are getting down, those small meals will increase it again and you will never see the leptin during day.

Also, as you had read, glocagon is released from liver as a backup energy after 3 hours, so if you eat something in this period, glacagon is never released, sugar stays in your liver, and in longer term, your liver becomes fat, which is dangerous for your liver.

This is the simplified way of explaining thing, if you go deeper, you will also see some complex mechanisms, but in general this is what happens.

Small meals increases your methobolism, which is correct BUT:
- The blood sugar and insulin always stays high.
- High methobolism and high insulin also helps the body to send more trigleseride to fat cells.
- It is not possible to burn fat while you are storing fat.
- High insulin causes fat liver and pancreas, high blood pressure.

If you want to burn fat, help your body to produce leptin and increase physical activity.